果蝇细胞中受热激诱导的低分子量RNA——I. 合成及其对蛋白质合成的影响
Low molecular weight RNA of Drosophila cells which is induced by heat shock--I. Synthesis and its effect on protein synthesis.
作者信息
Kawata Y, Fujiwara H, Ishikawa H
机构信息
Department of Biology, College of Arts and Sciences, University of Tokyo, Japan.
出版信息
Comp Biochem Physiol B. 1988;91(1):149-53. doi: 10.1016/0305-0491(88)90127-7.
PMID:2461833
Abstract
When Drosophila cells were heat shocked, low molecular weight RNA of a novel type was synthesized and accumulated in the cytoplasm. This RNA, which is about 320 nucleotides long, inhibited the translation of Drosophila mRNAs in rabbit reticulocyte lysate. It remains to be clarified whether this RNA is involved in the regulation mechanism of heat shock at the translational level.
摘要
当果蝇细胞受到热激时，一种新型的低分子量RNA在细胞质中合成并积累。这种RNA长度约为320个核苷酸，在兔网织红细胞裂解物中抑制果蝇mRNA的翻译。这种RNA是否参与热激在翻译水平的调控机制仍有待阐明。
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