阿育吠陀灰剂：纳米材料方面、应用和前景的概述。

Ayurvedic Bhasmas: overview on nanomaterialistic aspects, applications, and perspectives.

机构信息

Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal,

出版信息

Adv Exp Med Biol. 2014;807:23-32. doi: 10.1007/978-81-322-1777-0_3.

PMID:24619616

Abstract

In this paper, we present an overview of Ayurvedic Bhasmas as nanomedicine of herbo-metallic and mineral origin with particular attention to their structural aspects. We find, the Bhasmas as nanomedicines may offer a huge potential for designing new drugs employing the concept of nanotechnology. Thus, the standardization of fabrication process of these formulations is a crucial issue to be addressed. The structure and effectiveness of the Bhasmas as drugs depend largely on their processing history. Bhasmas are generally safe drugs for human beings in spite of the presence of seemingly toxic elements and compounds as indicated by recent studies using modern analytical techniques. Nevertheless, more systematic nanomaterialistic investigations on Bhasmas are recommended for gaining the complete and reliable composition-processing-structure-effectiveness picture of these drugs.

摘要

本文概述了源自草药和金属的阿育吠陀制剂（Bhasmas）如何作为纳米药物，特别关注它们的结构方面。我们发现，Bhasmas 作为纳米药物，可能为采用纳米技术概念设计新药提供巨大潜力。因此，这些制剂的制造工艺的标准化是需要解决的关键问题。Bhasmas 作为药物的结构和功效在很大程度上取决于其加工历史。尽管最近使用现代分析技术的研究表明，Bhasmas 中存在看似有毒的元素和化合物，但它们通常对人类是安全的药物。然而，建议对 Bhasmas 进行更系统的纳米材料研究，以全面了解这些药物的完整和可靠的组成-加工-结构-功效关系。