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通过两种不同方法合成及表征云母灰(云母煅灰)

Synthesis and characterization of Abhraka (mica) bhasma by two different methods.

作者信息

Kantak Shailesh, Rajurkar Nilima, Adhyapak Parag

机构信息

Department of Chemistry, Savitribai Phule Pune University, Pune, 411 007, India.

Department of Chemistry, Savitribai Phule Pune University, Pune, 411 007, India.

出版信息

J Ayurveda Integr Med. 2020 Jul-Sep;11(3):236-242. doi: 10.1016/j.jaim.2018.11.003. Epub 2019 Feb 28.

Abstract

BACKGROUND

Bhasmas are traditional Ayurvedic medicines prepared from minerals and metals by tedious process which removes toxic properties of metals and minerals and enhances medicinal properties. We have synthesized abhraka bhasma by two traditional methods and were analyzed during each stage of preparation.

OBJECTIVE

The present study deals with the synthesis and characterization of abhraka bhasma by two different methods, method-1 is commonly used for treating anemia and tropical sprue and method-2 for treating chronic cough. Hence attempts have been made to see the physico-chemical differences between these methods by using different analytical techniques.

MATERIAL AND METHODS

Different steps in preparation of abhraka bhasma includes shodhana (purification), dhanyabhraka, marana (incineration) and amritikarana. The prepared bhasma were analyzed by classical ayurvedic tests and modern analytical techniques like XRD, FTIR, Raman spectroscopy, SEM, TEM, EDX, BET, DLS and TGA/DTA.

RESULTS

The morphological characterization revealed that as-prepared abhraka bhasma products were nano crystalline in nature. Elemental analysis confirms presence of various elements along with carbon suggesting bhasma as herbo-mineral compound. The XRD studies revealed the presence of KMg(SiAl)O(OH) in bhasmas.

CONCLUSION

Characterization study revealed presence of various bonds of different functional groups and formation of nano particles. Abhraka bhasma prepared by method-2 has more proportion of nano particles than that prepared by method-1 and hence will be more effective in its use.

摘要

背景

煅灰制剂是传统的阿育吠陀药物,由矿物质和金属经繁琐工艺制备而成,该工艺可去除金属和矿物质的毒性并增强其药用特性。我们通过两种传统方法合成了云母煅灰制剂,并在制备的每个阶段进行了分析。

目的

本研究涉及通过两种不同方法合成和表征云母煅灰制剂,方法1常用于治疗贫血和热带口炎性腹泻,方法2用于治疗慢性咳嗽。因此,已尝试通过使用不同的分析技术来观察这些方法之间的物理化学差异。

材料与方法

云母煅灰制剂制备的不同步骤包括净化、稻糠云母、煅烧和甘露化。制备的煅灰制剂通过经典的阿育吠陀测试和现代分析技术进行分析,如X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)、拉曼光谱、扫描电子显微镜(SEM)、透射电子显微镜(TEM)、能谱分析(EDX)、比表面积分析(BET)、动态光散射(DLS)和热重分析/差示热分析(TGA/DTA)。

结果

形态表征显示,制备的云母煅灰制剂产品本质上是纳米晶体。元素分析证实除碳外还存在各种元素,表明煅灰制剂为草药-矿物化合物。XRD研究表明煅灰制剂中存在钾镁铝硅酸盐氢氧化物(KMg(SiAl)O(OH))。

结论

表征研究揭示了不同官能团的各种键的存在以及纳米颗粒的形成。方法2制备的云母煅灰制剂比方法1制备的含有更多比例的纳米颗粒,因此其使用效果会更显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5e1/7527821/4d002a000336/gr1.jpg

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