Stillwell T J, Malek R S, Engen D E, Farrow G M
Department of Urology, Mayo Clinic, Rochester, Minnesota 55905.
J Urol. 1989 Jan;141(1):76-8. doi: 10.1016/s0022-5347(17)40594-5.
Adenocarcinoma of the prostate occasionally is discovered incidentally in the enucleated gland at open prostatic adenectomy for benign disease. Among 468 men who underwent open prostatic adenectomy, unsuspected adenocarcinoma of the prostate was found on pathological examination in 28 (6.0 per cent). The tumors were stage A1 in 14 patients and stage A2 in 14. Careful tissue review resulted in reassigning 5 cases from stage A1 to stage A2. At a mean followup of 10.6 years disease progression had occurred in 4 patients with stage A2 disease. When stage A adenocarcinoma is discovered after open prostatectomy we recommend careful review of the surgical specimen for accurate staging, and adjuvant therapy for all patients with stage A2 disease an for younger patients (less than 65 years old) with stage A1 disease who have favorable life expectancies.
前列腺腺癌偶尔在因良性疾病接受开放性前列腺切除术摘除的腺体中被偶然发现。在468例行开放性前列腺切除术的男性中，28例（6.0%）经病理检查发现了意外的前列腺腺癌。其中14例患者的肿瘤为A1期，14例为A2期。经过仔细的组织复查，5例从A1期重新分类为A2期。平均随访10.6年时，4例A2期疾病患者出现了疾病进展。当开放性前列腺切除术后发现A期腺癌时，我们建议仔细检查手术标本以进行准确分期，对所有A2期疾病患者以及预期寿命良好的A1期疾病年轻患者（小于65岁）进行辅助治疗。
