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儿童侵袭性脑膜炎球菌病的临床特征和长期后遗症。

The clinical features and long-term sequelae of invasive meningococcal disease in children.

机构信息

From the *Jerusalem District Health Office, Ministry of Health; and †Braun School of Public Health and Community Medicine, Faculty of Medicine, Hebrew University and Hadassah, Jerusalem, Israel.

出版信息

Pediatr Infect Dis J. 2014 Jul;33(7):777-9. doi: 10.1097/INF.0000000000000282.

DOI:10.1097/INF.0000000000000282
PMID:24622347
Abstract

We evaluated the outcome of invasive meningococcal disease in children <15 years of age (n = 181). Neisseria meningitidis serogroup B comprised 78% of bacterial isolates. Case fatality rate was 11.6%. In follow-up interviews (115/160 survivors, 72%), at least 1 long-term sequela was reported in 38/115 children (33%), including learning-academic difficulties (22.6%), hearing impairment (7%), neurologic (12.2%), behavioral (14.8%) and motor (10.4%) deficits.

摘要

我们评估了 15 岁以下儿童侵袭性脑膜炎奈瑟菌病的结局(n = 181)。脑膜炎奈瑟菌 B 群占细菌分离株的 78%。病死率为 11.6%。在随访访谈中(160 名幸存者中的 115 名,72%),115 名儿童中有 38 名(33%)报告至少存在 1 种长期后遗症,包括学习-学术困难(22.6%)、听力损伤(7%)、神经(12.2%)、行为(14.8%)和运动(10.4%)缺陷。

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