Jensen K M, Jørgensen J B, Mogensen P
Department of Urology D, Bispebjerg Hospital, Copenhagen, Denmark.
Scand J Urol Nephrol Suppl. 1988;114:84-6.
In order to examine the prognostic role of routine urodynamic testing in prostatism, a prospective study was undertaken. The patients were selected for prostatic surgery exclusively by means of non-urodynamic criteria, but in addition an extensive, blinded urodynamic work-up was performed, including uroflowmetry, pressure-flow study combined with stop-flow test and water cystometry. The study comprised 139 patients consecutively referred for prostatism. Six months postoperatively all patients were reexamined. Previously the preoperative urodynamic data from each modality were analysed separately. In an attempt to increase the prognostic information, all data were computed simultaneously using linear discriminant analysis. Several preoperative variables appeared valuable to discriminate between patients with favourable and unfavourable postoperative outcome, respectively. However, the results of classification employing even the best combinations of variables did not result in more than 88% of the patients being correctly classified. Furthermore, especially the patients with unfavourable outcome generally were misclassified. Several reasons for this lack of efficacy are briefly mentioned, including the great overlap in preoperative urodynamic data between patients with favourable and unfavourable postoperative outcome and the relatively low postoperative failure rate.
为了研究常规尿动力学检查在前列腺增生症中的预后作用，我们进行了一项前瞻性研究。患者仅通过非尿动力学标准入选前列腺手术，但此外还进行了广泛的、盲法的尿动力学检查，包括尿流率测定、压力-流率研究结合憋尿试验和水囊测压法。该研究纳入了139例因前列腺增生症连续转诊的患者。术后6个月对所有患者进行复查。此前，对每种检查方式的术前尿动力学数据进行了单独分析。为了增加预后信息，使用线性判别分析同时计算所有数据。几个术前变量分别对于区分术后预后良好和不良的患者似乎很有价值。然而，即使采用最佳变量组合进行分类，结果也未能使超过88%的患者被正确分类。此外，尤其是预后不良的患者通常被错误分类。简要提及了这种缺乏有效性的几个原因，包括术后预后良好和不良的患者术前尿动力学数据有很大重叠以及术后失败率相对较低。
