Jensen K M, Jørgensen J B, Mogensen P
Department of Urology D, Bispebjerg Hospital, Copenhagen, Denmark.
Scand J Urol Nephrol Suppl. 1988;114:72-7.
In a prospective study the prognostic value of preoperative pressure-flow studies in prostatism was examined. The indications for prostatectomy were based on non-urodynamic data only. An extensive urodynamic evaluation was performed pre- and postoperatively, including uroflowmetry, water cystometry and pressure-flow study combined with stop-flow test. In total the data from 130 patients were considered. The material was classified with respect to the "urethral resistance relation" (URR) and the "bladder output relation" (BOR). According to the first criterion 87 patients were obstructed, 36 unobstructed, while 7 were unclassifiable and finally excluded. In most urodynamic variables, the two groups differed preoperatively, but no differences were revealed postoperatively. However, the obstructed group did considerably better postoperatively as to the symptomatic outcome. The success rate was 93% as opposed to 78% in the unobstructed patients (p less than 0.02). For the BOR classification, the theoretical maximum flow rate (Qm,est) was employed forming two groups: 57 patients with decreased bladder speed (Qm,est less than 35 ml/sec) and 41 patients with normal speed (Qm,est greater than or equal to 35 ml/sec). Few differences in urodynamic variables were found both pre- and postoperatively, but no significant difference was shown in success rates. In conclusion the URR proved a significant prognostic value in prostatism and is recommended in the preoperative work-up, especially in patients with equivocal uroflow studies. No convincing prognostic role could be attributed to the BOR.
在一项前瞻性研究中,对术前压力-流量研究在前列腺增生症中的预后价值进行了检查。前列腺切除术的指征仅基于非尿动力学数据。术前和术后均进行了广泛的尿动力学评估,包括尿流率测定、水囊测压法以及结合停止-流动试验的压力-流量研究。总共考虑了130例患者的数据。根据“尿道阻力关系”(URR)和“膀胱输出关系”(BOR)对资料进行分类。根据第一个标准,87例患者存在梗阻,36例无梗阻,而7例无法分类,最终被排除。在大多数尿动力学变量方面,两组术前存在差异,但术后未发现差异。然而,就症状结果而言,梗阻组术后情况明显更好。成功率为93%,而无梗阻患者为78%(p小于0.02)。对于BOR分类,采用理论最大流速(Qm,est)分为两组:57例膀胱速度降低的患者(Qm,est小于35毫升/秒)和41例速度正常的患者(Qm,est大于或等于35毫升/秒)。术前和术后在尿动力学变量方面几乎没有发现差异,但成功率没有显著差异。总之,URR在前列腺增生症中被证明具有显著的预后价值,建议在术前检查中使用,尤其是在尿流研究结果不明确的患者中。BOR未显示出令人信服的预后作用。