Rendell Simon
Emerg Med J. 2014 Apr;31(4):331-7. doi: 10.1136/emermed-2014-203646.1.
A short-cut review was carried out to determine whether the International Normalised Ratio (INR) value was a predictor of the risk of intracranial haemorrhage in patients taking warfarin after head injury. 796 papers were found using the reported search, of which eighteen were directly relevant. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses are shown in the accompanying table. It is concluded that level of the INR correlates poorly with the risk of haemorrhage and that the risk of haemorrhage remains significant even in patients with a sub-therapeutic INR.
进行了一项简短综述，以确定国际标准化比值（INR）是否为头部受伤后服用华法林患者颅内出血风险的预测指标。通过报告的检索方式共找到796篇论文，其中18篇直接相关。随附表格展示了作者、出版日期和国家、所研究的患者群体、研究类型、相关结局、结果及研究不足。得出的结论是，INR水平与出血风险的相关性较差，即使INR低于治疗水平，出血风险仍然很大。
