[Acceptance of amino acids by transfer RNA in the liver of rabbits in experimental diabetes complicated by glucocorticoid administration].

Alloxan diabetic rabbits were injected with hydrocortisone acetate (1 mg/kg) daily for one week. This led to a more pronounced decrease of acception of 14C-lysine, 14C-alanine, and 14C-leucine by tRNAs as compared to the diabetic status. Diminution of formation of aminoacyl-tRNA in the liver of diabetic animals was the result not only of insulin deficiency, but also of the negative action of glucocorticoids.