Isaev P A, Il'in A A, Medvedev V S, Semin D Iu, Pol'kin V V, Derbugov D N, Vasil'kov S V, Radzhanova M U, Chebotareva I V
Vopr Onkol. 2013;59(6):781-4.
The paper analyzes the effectiveness of external beam radiation therapy of medullary thyroid cancer in 38 patients. The radiation therapy of the first phase combined therapy was performed in 9 (24 %) patients: after treatment, 5 patients had a partial response, 4--stabilization. The radiation therapy of the second phase combined therapy was performed in 27 (71%) patients: after treatment, 2 patients had a complete response (booster method), 5--partial response, 4--stabilization. External beam therapy has been performed in 2 (5 %) patients with palliative and symptomatic goals. Additionally has been estimated level of calcitonin in patients after combined treatment. The calcitonin level becomes normal without radiation therapy. Therefore, exposure for medullary thyroid carcinoma is questionable (exception for cases gain exposure to the rest of the tumor).
本文分析了38例甲状腺髓样癌患者接受外照射放疗的疗效。9例(24%)患者进行了第一阶段联合治疗的放疗:治疗后,5例患者部分缓解,4例病情稳定。27例(71%)患者进行了第二阶段联合治疗的放疗:治疗后,2例患者完全缓解(强化法),5例部分缓解,4例病情稳定。2例(5%)患者为姑息和对症目的进行了外照射治疗。此外,还评估了联合治疗后患者的降钙素水平。未进行放疗时降钙素水平恢复正常。因此,甲状腺髓样癌的照射治疗存在疑问(除暴露于肿瘤其他部位的情况外)。