Department of Organic Chemistry, Omsk F. M. Dostoevsky State University , Mira Ave., 55a, 644077 Omsk, Russia.
Org Lett. 2014 Apr 4;16(7):1833-5. doi: 10.1021/ol500356w. Epub 2014 Mar 13.
A simple and efficient approach is developed for the synthesis of substituted 2,2'-bithiophene- and 2,2':5',2″-terthiophene-5-carboxylic acids and esters which is based on thiophene ring closure in the Fiesselmann reaction. Using this method, derivatives containing a long alkyl chain with or without an end functional group or an aryl substituent can be conveniently prepared.
开发了一种简单高效的方法，用于合成取代的 2,2'-联噻吩-和 2,2':5',2″-三噻吩-5-羧酸及其酯，该方法基于菲舍尔曼反应中环噻吩的闭环反应。使用这种方法，可以方便地制备含有长烷基链的衍生物，无论是否带有末端官能团或芳基取代基。
