Adagra Carl, Foster Darren J
School of Veterinary and Biomedical Sciences, James Cook University, Townsville, QLD, Australia
Eastside Vet Emergency and Specialists, Rose Bay, Sydney, NSW, Australia.
J Feline Med Surg. 2015 Feb;17(2):168-72. doi: 10.1177/1098612X14527083. Epub 2014 Mar 13.
Hyperammonaemia is well reported in animals with advanced hepatic disease and portosystemic shunts, but is unreported in cats with renal disease. This case series describes four cats with severe renal azotaemia in which elevated ammonia levels were detected during the course of treatment. In two cases hyperammonaemia was detected at a time when neurological signs consistent with encephalopathy had developed. This raises the possibility that hyperammonaemia may play a role in the development of encephalopathy in cats with renal azotaemia.
高氨血症在患有晚期肝病和门体分流的动物中已有充分报道,但在患有肾病的猫中未见报道。本病例系列描述了四只患有严重肾性氮血症的猫,在治疗过程中检测到其氨水平升高。在两例病例中,当出现与脑病一致的神经症状时检测到高氨血症。这增加了高氨血症可能在肾性氮血症猫的脑病发展中起作用的可能性。