van den Broek Emke Mechelina Josephina Margo, van der Zaag-Loonen Hester Josephine, Bruintjes Tjasse Doewe
Apeldoorn Dizziness Centre, Gelre Hospital, Apeldoorn, The Netherlands
Apeldoorn Dizziness Centre, Gelre Hospital, Apeldoorn, The Netherlands.
Otolaryngol Head Neck Surg. 2014 Jun;150(6):933-8. doi: 10.1177/0194599814525919. Epub 2014 Mar 13.
In this rapid systematic review, we studied the efficacy of the Gufoni maneuver for the treatment of lateral canal benign paroxysmal positional vertigo (BPPV) with geotropic nystagmus.
A comprehensive search, including PubMed, Embase, Web of Science, and Cochrane as data sources, resulted in 44 original papers for randomized trials that compared the Gufoni maneuver with other maneuvers (date of search: April 23, 2013). Three studies (389 patients) remained after screening of title, abstract, and full text.
After method assessment, 2 of these 3 studies were considered to have a low risk of bias and a high level of validity. The third study did not properly report the treatment allocation and blinding; moreover, outcome data were incomplete. The first 2 studies compared the Gufoni maneuver with a sham maneuver (and the barbecue roll in one study). The third study compared the Gufoni maneuver with a treatment with vestibular suppressants and with the barbecue roll (plus forced prolonged positioning). All 3 studies reported short-term results. Midterm results (1 month) were reported in 2 studies.
Given the variety in the comparative treatments and follow-up duration, all 3 studies showed that the Gufoni maneuver was more effective than the sham maneuver or treatment with vestibular suppressants. All agreed that the maneuver was easy to perform, which made it suitable for older, immobile, and obese patients. However, there were insufficient data to establish the relative efficacy of the Gufoni maneuver compared with other maneuvers.
在本快速系统评价中,我们研究了古福尼手法治疗伴有地向性眼震的水平半规管良性阵发性位置性眩晕(BPPV)的疗效。
以PubMed、Embase、科学网和考克兰图书馆作为数据来源进行全面检索,共获得44篇比较古福尼手法与其他手法的随机试验原始论文(检索日期:2013年4月23日)。经标题、摘要和全文筛选后,保留3项研究(389例患者)。
经方法学评估,这3项研究中的2项被认为偏倚风险低且效度高。第3项研究未正确报告治疗分配和设盲情况;此外,结局数据不完整。前2项研究将古福尼手法与假手法(其中1项研究还与翻滚试验)进行了比较。第3项研究将古福尼手法与使用前庭抑制剂的治疗以及翻滚试验(加强迫性延长体位)进行了比较。所有3项研究均报告了短期结果。2项研究报告了中期(1个月)结果。
鉴于比较治疗方法和随访时间的差异,所有3项研究均表明,古福尼手法比假手法或使用前庭抑制剂的治疗更有效。所有研究均认为该手法易于实施,适用于老年、行动不便和肥胖患者。然而,与其他手法相比,尚无足够数据确定古福尼手法的相对疗效。