Takada H, Mikawa T, Murayama M, Sugai J, Yamamura Y
Department of Second Internal Medicine, St. Marianna University, School of Medicine, Kanagawa, Japan.
Am J Cardiol. 1989 Jan 15;63(3):184-6. doi: 10.1016/0002-9149(89)90282-8.
The incidence and forms of ventricular premature complexes (VPCs) in apparently healthy subjects were studied to determine long-term reproducibility of day to day variation on Holter electrocardiogram. The study included 152 men and 68 women ranging in age from 20 to 78 years who were having routine check-ups that revealed no cardiovascular abnormalities. In addition to routine measurements, Holter electrocardiography was recorded during daily life, and the total number of VPCs occurring during 24 hours was visually calculated on replayed electrocardiographic tracings. Forms of VPCs and incidence of VPCs in 10-year age groups of the subjects were also recorded. No VPCs were observed in 56% of the subjects; 93% showed less than 50 VPCs and the other 7% of the 220 subjects had greater than or equal to 50 VPCs. Forty-one of the 220 subjects returned for routine follow-up 1 year later. Repeated Holter electrocardiograms at this time showed high reproducibility of less than 50 VPCs. A small number of multiform VPCs were reproducible but paired VPCs were not. Physiologic definition of VPCs in healthy subjects appears to be clinically significant.
研究了貌似健康的受试者室性早搏（VPC）的发生率和形式，以确定动态心电图（Holter）上每日变化的长期可重复性。该研究纳入了152名男性和68名女性，年龄在20至78岁之间，他们在进行常规体检时未发现心血管异常。除常规测量外，在日常生活中记录动态心电图，通过回放心电图记录直观计算24小时内发生的VPC总数。还记录了受试者10岁年龄组的VPC形式和VPC发生率。56%的受试者未观察到VPC；93%的受试者VPC少于50次，220名受试者中的另外7%的VPC大于或等于50次。220名受试者中有41名在1年后返回进行常规随访。此时重复的动态心电图显示少于50次VPC具有高度可重复性。少数多形性VPC可重复，但成对VPC不可重复。健康受试者VPC的生理学定义似乎具有临床意义。
