在丙烯酰氯存在下，通过伯胺与苯基异硫氰酸酯反应便捷地合成2-亚氨基-1,3-噻嗪-4-酮衍生物。
A convenient synthesis of 2-imino-1,3-thiazine-4-one derivatives from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride.
作者信息
Zolali Amin, Nasiri Farough, Omid-Niakan Sonia
机构信息
Department of Chemistry, Faculty of Science, University of Kurdistan, Sanandaj, Iran.
出版信息
Comb Chem High Throughput Screen. 2014;17(7):610-3. doi: 10.2174/1386207317666140313110334.
Abstract
An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.
摘要
描述了一种高效、一锅法且三组分的合成具有生物学重要性的杂环化合物的方法，该方法是在室温下，在丙烯酰氯存在下，伯胺与异硫氰酸苯酯反应，无需使用任何催化剂。
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