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Compassionate use of vismodegib and adjuvant radiotherapy in the treatment of multiple locally advanced and inoperable basal cell carcinomas and squamous cell carcinomas of the skin.

作者信息

Gathings Robert M, Orscheln Courtney S, Huang William W

机构信息

Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina.

出版信息

J Am Acad Dermatol. 2014 Apr;70(4):e88-e89. doi: 10.1016/j.jaad.2013.11.032.

DOI:10.1016/j.jaad.2013.11.032
PMID:24629372
Abstract
摘要

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1
Compassionate use of vismodegib and adjuvant radiotherapy in the treatment of multiple locally advanced and inoperable basal cell carcinomas and squamous cell carcinomas of the skin.维莫德吉的同情用药及辅助放疗在治疗多发性局部晚期且无法手术切除的皮肤基底细胞癌和鳞状细胞癌中的应用
J Am Acad Dermatol. 2014 Apr;70(4):e88-e89. doi: 10.1016/j.jaad.2013.11.032.
2
Two different scenarios of squamous cell carcinoma within advanced Basal cell carcinomas: cases illustrating the importance of serial biopsy during vismodegib usage.两种不同的高级基底细胞癌中鳞状细胞癌的情况：说明在使用维莫德吉期间进行连续活检重要性的病例。
JAMA Dermatol. 2014 Sep;150(9):970-3. doi: 10.1001/jamadermatol.2014.583.
3
Epidermal cyst formation and hyperkeratosis in a patient treated with vismodegib for locally advanced Basal cell carcinoma.一名接受维莫德吉治疗局部晚期基底细胞癌的患者出现表皮囊肿形成和角化过度。
Acta Derm Venereol. 2015 May;95(5):618-9. doi: 10.2340/00015555-2020.
4
Pivotal ERIVANCE basal cell carcinoma (BCC) study: 12-month update of efficacy and safety of vismodegib in advanced BCC.Erivance 关键性基底细胞癌（BCC）研究：维莫德吉治疗晚期 BCC 的疗效和安全性 12 个月更新。
J Am Acad Dermatol. 2015 Jun;72(6):1021-6.e8. doi: 10.1016/j.jaad.2015.03.021.
5
Vismodegib in the treatment of advanced BCC.维莫德吉用于治疗晚期基底细胞癌。
Ir Med J. 2014 Jul-Aug;107(7):215-6.
6
Concurrent Vismodegib and Radiotherapy for Recurrent, Advanced Basal Cell Carcinoma.维莫德吉与放疗联合治疗复发性、晚期基底细胞癌。
JAMA Dermatol. 2015 Sep;151(9):998-1001. doi: 10.1001/jamadermatol.2015.0326.
7
Vismodegib and surgery combined - effective treatment of locally advanced basal cell carcinoma.维莫德吉与手术联合——局部晚期基底细胞癌的有效治疗方法
Acta Oncol. 2016 Dec;55(12):1492-1494. doi: 10.1080/0284186X.2016.1206212. Epub 2016 Jul 22.
8
Identifying locally advanced basal cell carcinoma eligible for treatment with vismodegib: an expert panel consensus.确定适合用维莫德吉治疗的局部晚期基底细胞癌：专家小组共识
Future Oncol. 2015;11(4):703-12. doi: 10.2217/fon.14.281.
9
Multiple highly and moderately differentiated squamous cell carcinomas of the skin during vismodegib treatment of inoperable basal cell carcinoma.在使用维莫德吉治疗无法手术的基底细胞癌期间出现的多个高分化和中分化皮肤鳞状细胞癌。
Br J Dermatol. 2014 Aug;171(2):431-3. doi: 10.1111/bjd.12840. Epub 2014 Aug 2.
10
Two intermittent vismodegib dosing regimens in patients with multiple basal-cell carcinomas (MIKIE): a randomised, regimen-controlled, double-blind, phase 2 trial.两种间断维莫德吉给药方案治疗多发性基底细胞癌患者（MIKIE）：一项随机、方案对照、双盲、2 期试验。
Lancet Oncol. 2017 Mar;18(3):404-412. doi: 10.1016/S1470-2045(17)30072-4. Epub 2017 Feb 8.

引用本文的文献

1
Phase II, Single-Arm Trial of Induction and Concurrent Vismodegib With Curative-Intent Radiation Therapy for Locally Advanced, Unresectable Basal Cell Carcinoma.诱导治疗联合维莫德吉与根治性放疗治疗局部晚期不可切除基底细胞癌的 II 期单臂试验。
J Clin Oncol. 2024 Jul 1;42(19):2327-2335. doi: 10.1200/JCO.23.01708. Epub 2024 Apr 17.
2
Pathologic complete response with radiation and vismodegib in a patient with advanced basal cell carcinoma: A case report.晚期基底细胞癌患者经放疗和维莫德吉治疗后达到病理完全缓解：一例报告
Mol Clin Oncol. 2021 Mar;14(3):46. doi: 10.3892/mco.2021.2208. Epub 2021 Jan 13.
3
New developments in the treatment of basal cell carcinoma: update on current and emerging treatment options with a focus on vismodegib.
基底细胞癌治疗的新进展：聚焦维莫德吉的当前及新兴治疗选择的最新情况
Onco Targets Ther. 2018 Nov 23;11:8327-8340. doi: 10.2147/OTT.S135650. eCollection 2018.
4
Combination Trimodality Therapy Using Vismodegib for Basal Cell Carcinoma of the Face.使用维莫德吉的三联疗法治疗面部基底细胞癌
Case Rep Oncol Med. 2015;2015:827608. doi: 10.1155/2015/827608. Epub 2015 Oct 4.
5
Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome.Sonic Hedgehog（Shh）信号与p50/Bcl3信号的相互作用驱动了基底细胞癌综合征中基底细胞癌的发病机制。
Oncotarget. 2015 Nov 3;6(34):36789-814. doi: 10.18632/oncotarget.5103.