Dahl Knudsen Jenny, Frimodt-Møller Niels
Klinisk Mikrobiologisk Afdeling, Hvidovre Hospital, Kettegaard Alle 30, 2650 Hvidovre.
Ugeskr Laeger. 2013 Nov 18;175(47):2854-7.
Antibiotic treatment of elderly patients implies special problems because of higher probability of reduced renal or other organ function, and interactions with other medications. Elderly patients are more often previously hospitalised and treated with antibiotics or live in health-care institutions, and may be colonised with resistant microorganisms. It is crucial to sample for microbiological diagnostics before therapy. Adverse effects of antibiotics are seen more frequently with increasing age. Otherwise, the effect of antibiotics and durations of therapy is independent of patient age.
老年患者的抗生素治疗存在特殊问题，因为其肾功能或其他器官功能减退的可能性更高，且会与其他药物发生相互作用。老年患者既往更常住院并接受抗生素治疗，或居住在医疗机构中，可能感染耐药微生物。治疗前进行微生物学诊断采样至关重要。抗生素的不良反应随年龄增长更为常见。此外，抗生素的疗效和治疗持续时间与患者年龄无关。
