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局部晚期癌症患者新辅助化疗后保乳手术。初步结果。

Breast-conserving surgery after neoadjuvant chemotherapy in patients with locally advanced cancer. Preliminary results.

作者信息

Vergine M, Scipioni P, Garritano S, Colangelo M, Di Paolo A, Livadoti G, Maturo A, Monti M

出版信息

G Chir. 2013 Sep-Oct;34(9-10):254-6.

PMID:24629809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3926477/
Abstract

Neoadjuvant chemotherapy (NACT) in locally advanced breast tumors may allow an adequate control of the disease impossible with surgery alone. Moreover, NACT increases the chance of breast-conserving surgery. Between 2008 and 2012, we treated with NACT 83 patients with locally advanced breast cancer. We report the preliminary results evaluating the impact of NACT on the type of surgery.

摘要

新辅助化疗（NACT）用于局部晚期乳腺肿瘤，可能实现仅靠手术无法充分控制的疾病控制效果。此外，新辅助化疗增加了保乳手术的机会。2008年至2012年期间，我们对83例局部晚期乳腺癌患者进行了新辅助化疗。我们报告评估新辅助化疗对手术类型影响的初步结果。

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The ratio of positive to excised nodes identifies high-risk subsets and reduces inter-institutional differences in locoregional recurrence risk estimates in breast cancer patients with 1-3 positive nodes: an analysis of prospective data from British Columbia and the M. D. Anderson Cancer Center.阳性淋巴结与切除淋巴结的比例可识别高危亚组，并减少1-3个阳性淋巴结的乳腺癌患者局部区域复发风险估计中的机构间差异：来自不列颠哥伦比亚省和MD安德森癌症中心的前瞻性数据分析。
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Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials.接受乳房切除术及辅助化疗（使用或不使用他莫昔芬且未进行放疗）治疗的可手术乳腺癌患者的局部区域复发模式：五项国家外科辅助乳腺和肠道项目随机临床试验的结果
J Clin Oncol. 2004 Nov 1;22(21):4247-54. doi: 10.1200/JCO.2004.01.042. Epub 2004 Sep 27.
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