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微创心脏手术时代迷你体外循环的“益处”

The "benefits" of the mini-extracorporeal circulation in the minimal invasive cardiac surgery era.

作者信息

Baikoussis Nikolaos G, Papakonstantinou Nikolaos A, Apostolakis Efstratios

机构信息

Cardiac Surgery Department, Institut Mutualiste Montsouris, Paris, 75014, France.

Cardiac Surgery Department, Ioannina University, School of Medicine, Ioannina, 45500, Greece.

出版信息

J Cardiol. 2014 Jun;63(6):391-6. doi: 10.1016/j.jjcc.2013.12.014. Epub 2014 Mar 12.

Abstract

Mini-extracorporeal circulation (MECC) constitutes a novel miniaturized cardiopulmonary bypass (CPB) circuit, heparin-coated and primed with aprotinin. Its membrane oxygenation is similar to conventional cardio-pulmonary bypass (CCPB), but it is a completely closed-volume system due to the lack of the venous reservoir which has been removed. In a mini circuit, the reservoir is the patient himself. Consequently, air entering the venous cannula is avoided. Nevertheless, the capabilities of MECC have been expanded either by the inclusion of a suction device that is only activated on direct contact with liquid in some circuits or by postoperative autotransfusion of the wrecked erythrocytes by a separate suction device with a cell-saver. Although the tubing diameter is similar between the two systems, the tubing length of the MECC is around half that of the CCPB, resulting in the restriction of priming volume. As a consequence, a higher hematocrit thus a limited need for perioperative blood transfusion is achieved due to less hemodilution. In addition, the inflammatory response is also diminished as a result of less artificial surface area interacting with blood. Finally, a lower dose of heparin is required prior to MECC than prior to CCPB.

摘要

微型体外循环(MECC)是一种新型的小型化心肺转流(CPB)回路,采用肝素涂层并以抑肽酶预充。其膜式氧合与传统心肺转流(CCPB)相似,但由于去除了静脉贮血器,它是一个完全封闭的容量系统。在微型回路中,贮血器就是患者自身。因此,可避免空气进入静脉插管。然而,MECC的功能已通过以下方式得到扩展:在某些回路中加入仅在与液体直接接触时才启动的吸引装置,或者通过带有细胞回收器的单独吸引装置对破碎红细胞进行术后自体输血。尽管两个系统的管道直径相似,但MECC的管道长度约为CCPB的一半,这导致预充量受到限制。结果,由于血液稀释较少,可实现更高的血细胞比容,从而减少围手术期输血需求。此外,由于与血液相互作用的人工表面积较小,炎症反应也会减轻。最后,MECC术前所需的肝素剂量低于CCPB术前。

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