Kjer Jens Jørgen, Kristensen Jens, Hartwell Dorthe, Jensen Marianne Aamann
Department of Obstetrics and Gynaecology, Rigshospitalet, University Hospital, Denmark.
Department of Gynaecology and Obstetrics, Herlev University Hospital, Denmark.
Eur J Obstet Gynecol Reprod Biol. 2014 May;176:31-3. doi: 10.1016/j.ejogrb.2014.02.018. Epub 2014 Feb 20.
To draw attention to the rare condition of endometriosis in the bladder. This is correlated with symptoms not normally connected to endometriosis and therefore often remains underdiagnosed for years.
Retrospective study in a university teaching hospital, one of two referral centres in Denmark for surgical treatment of stage III and IV endometriosis.
Thirty-one women with deep infiltrating bladder endometriosis.
All women presenting in the Department of Obstetrics and Gynaecology with deep infiltrating bladder endometriosis between March 2002 and March 2011. We included only patients with symptomatic full-thickness bladder detrusor endometriosis and mucosal involvement. All patients had had bladder symptoms for two to seven years.
Symptoms after surgery and recurrence rate.
The main preoperative symptom was urinary frequency. All patients had significant relief of symptoms after operation, and none had recurrence of the bladder endometriosis judged by ultrasound or reported symptoms. Twenty-six (87%) patients had endometriosis in another location as well. Eight had nodules in the recto-vaginal septum. Complete surgical excision of all associated endometriotic lesions was carried out during the same surgical procedure. During the mean follow-up period of 59 months no long-term complications were diagnosed.
Bladder endometriosis should be considered in patients who present with irritative urological symptoms with aggravation during menstruation or in patients with a history of endometriosis. When patients have symptoms we recommend surgical treatment in cases where medical treatment fails.
引起人们对膀胱子宫内膜异位症这种罕见病症的关注。该病症与通常和子宫内膜异位症无关的症状相关,因此多年来常常未得到充分诊断。
在一所大学教学医院进行的回顾性研究,该医院是丹麦两个针对III期和IV期子宫内膜异位症进行手术治疗的转诊中心之一。
31名患有深部浸润性膀胱子宫内膜异位症的女性。
纳入2002年3月至2011年3月期间在妇产科就诊的所有患有深部浸润性膀胱子宫内膜异位症的女性。我们仅纳入有症状的全层膀胱逼尿肌子宫内膜异位症且伴有黏膜受累的患者。所有患者出现膀胱症状已有两到七年。
术后症状及复发率。
术前主要症状为尿频。所有患者术后症状均有明显缓解,通过超声检查或报告的症状判断,无一例膀胱子宫内膜异位症复发。26名(87%)患者在其他部位也患有子宫内膜异位症。8名患者在直肠阴道隔有结节。在同一次手术过程中对所有相关子宫内膜异位病变进行了完整的手术切除。在平均59个月的随访期内,未诊断出长期并发症。
对于出现刺激性泌尿系统症状且在月经期间加重的患者或有子宫内膜异位症病史的患者,应考虑膀胱子宫内膜异位症。当患者出现症状时,我们建议在药物治疗失败的情况下进行手术治疗。