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膀胱子宫内膜异位症:腹腔镜手术后的结果。

Endometriosis of bladder: outcomes after laparoscopic surgery.

机构信息

IRCAD (Research Institute Against Digestive Cancer) and University Hospitals Strasbourg (Hautepierre Hospital and CMCO [Centre Medico-Chirurgical et Obstetrical] Hospital), Strasbourg, France.

出版信息

J Minim Invasive Gynecol. 2010 Sep-Oct;17(5):600-4. doi: 10.1016/j.jmig.2010.05.008. Epub 2010 Jul 24.

Abstract

STUDY OBJECTIVE

To describe outcomes after laparoscopic excision of deep bladder endometriosis.

DESIGN

Retrospective study (Canadian Task Force classification II-3).

SETTING

University hospitals.

PATIENTS

Twenty-one consecutive patients with endometriotic nodule on the bladder (infiltrating detrusor muscle) from a series of 169 patients were included in the study. The primary outcome studied was resolution of bladder symptoms. Secondary outcomes included complication rates, recurrence rates, and pregnancy rates after laparoscopic surgery.

INTERVENTIONS

Laparoscopic excision of bladder endometriosis.

MEASUREMENTS AND MAIN RESULTS

Laparoscopy was feasible in all cases without the need for conversion. Median follow-up was 20 months. Ten patients (47.6%) underwent partial cystectomy, and the remaining patients underwent partial-thickness excision of the detrusor muscle. Sixteen patients (76%) had associated deep lesions in the pelvis. The most common associated lesions were rectovaginal nodules (38%) and ureteric lesions (14%), with signs of obstruction. Major complications developed in 3 patients (14%), primarily related to bowel resection. Six patients became pregnant (60%). No patients experienced disease recurrence.

CONCLUSION

Laparoscopic excision is feasible in all types of bladder endometriosis but often involves multiple procedures to manage associated lesions, especially rectovaginal nodules and ureteric lesions. Previous reports have suggested that ureteric lesions are not associated with bladder endometriosis; however, this was not true in our series. Complications are primarily related to severity of the disease and associated procedures. Partial cystectomy is not required in all cases to achieve adequate clearance. Complete excision of the disease is associated with resolution of bladder symptoms and low recurrence rates.

摘要

研究目的

描述腹腔镜下切除深部膀胱子宫内膜异位症的结果。

设计

回顾性研究(加拿大任务组分类 II-3)。

设置

大学医院。

患者

从 169 例患者中,共有 21 例连续患者(累及逼尿肌)的膀胱子宫内膜异位症结节纳入研究。主要研究结果为膀胱症状的缓解。次要结果包括腹腔镜手术后的并发症发生率、复发率和妊娠率。

干预措施

腹腔镜下切除膀胱子宫内膜异位症。

测量和主要结果

所有病例均可行腹腔镜手术,无需转换。中位随访时间为 20 个月。10 例(47.6%)患者行部分膀胱切除术,其余患者行逼尿肌部分厚度切除术。16 例患者(76%)存在盆腔深部病变。最常见的合并病变为直肠阴道结节(38%)和输尿管病变(14%),伴有梗阻迹象。3 例患者(14%)发生严重并发症,主要与肠切除术有关。6 例患者怀孕(60%)。无患者出现疾病复发。

结论

腹腔镜切除适用于所有类型的膀胱子宫内膜异位症,但通常需要多种程序来处理相关病变,尤其是直肠阴道结节和输尿管病变。既往报告提示输尿管病变与膀胱子宫内膜异位症无关;然而,我们的研究结果并非如此。并发症主要与疾病的严重程度和相关程序有关。并非所有病例都需要行部分膀胱切除术以达到充分的清除。彻底切除病变与膀胱症状缓解和低复发率相关。

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