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盐酸四环素作为脊椎动物和无脊椎动物髓鞘膜快速荧光染色剂的应用。

The use of tetracycline hydrochloride as a rapid fluorescent stain for myelin membranes in vertebrates and invertebrates.

作者信息

Pereyra P M, Roots B I

机构信息

Department of Zoology, University of Toronto, Ont., Canada.

出版信息

Brain Res. 1988 Aug 23;458(2):377-82. doi: 10.1016/0006-8993(88)90482-9.

DOI:10.1016/0006-8993(88)90482-9
PMID:2463053
Abstract

We report here the use of tetracycline as a fast and reliable histological stain of myelinated nerves. These results are significant in that they point to tetracyclines as potentially important probes to study the role of divalent and trivalent cations in myelinated nerves. The usefulness and specificity of tetracycline as a supravital probe for calcium and iron metabolism in myelinated nerves is currently under study.

摘要

我们在此报告四环素作为一种快速且可靠的有髓神经组织学染色剂的应用。这些结果意义重大,因为它们表明四环素可能是研究二价和三价阳离子在有髓神经中作用的重要探针。目前正在研究四环素作为有髓神经中钙和铁代谢的超活探针的实用性和特异性。

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