Department of Cardiothoracic Surgery, Ain Shams University, Cairo, Egypt.
Department of Cardiothoracic Surgery, Ain Shams University, Cairo, Egypt.
Ann Thorac Surg. 2014 May;97(5):1624-9. doi: 10.1016/j.athoracsur.2013.10.067. Epub 2014 Mar 13.
Cardiac surgery during pregnancy is reserved for cases of failure of medical treatment due to its detrimental maternal and fetal effects.
Between March 2003 and December 2012, 23 pregnant women with severe valve malfunction required open heart surgery. The mean age was 30.3±4.9 years. Gestational age ranged from 14 to 39 weeks. Twenty patients (87%) presented with signs of right ventricular failure. The main presenting lesion was severe aortic stenosis in 3 patients (13%), mitral stenosis in 3 patients (13%), and stuck mechanical mitral valve prosthesis in 17 patients (73.9%).
Fourteen patients were operated upon on emergency basis, and 9 patients on urgent basis. Two patients have continued their pregnancy to full term after cardiac surgery. Delivery was done immediately before surgery in 11 patients (47.8%). There were 10 intrauterine fetal deaths, all at gestational age below 28 weeks, 4 were confirmed before induction of anesthesia and 6 after surgery. There were 13 surviving babies, 7 premature babies (30.4%), and 6 full term babies (26.1%). Neonatal complications included respiratory distress syndrome in (38.5%) and prolonged hospital stay (46.2%). Maternal hospital morbidities included oliguria (65.2%), bleeding (30.4%), prolonged intensive care stay (56.5%), and prolonged hospital stay (26.2%). The in-hospital mortality was 8.7%.
Urgent and emergency valve replacement in pregnant women can be achieved with good maternal morbidity and mortality; however, high incidence of fetal losses might be expected when surgery is performed at an early gestational age.
由于对母婴均有不良影响,心脏手术仅在药物治疗失败的情况下用于妊娠女性。
2003 年 3 月至 2012 年 12 月期间,23 例患有严重瓣膜功能障碍的孕妇需要进行心脏直视手术。平均年龄为 30.3±4.9 岁。妊娠周数为 14 至 39 周。20 例(87%)患者出现右心室衰竭的迹象。主要病变为 3 例(13%)严重主动脉瓣狭窄、3 例(13%)二尖瓣狭窄和 17 例(73.9%)机械二尖瓣置换术后卡瓣。
14 例患者紧急手术,9 例患者紧急手术。2 例患者在心脏手术后继续妊娠至足月。11 例(47.8%)患者在手术前立即分娩。有 10 例宫内胎儿死亡,均发生在 28 周前,其中 4 例在麻醉诱导前确诊,6 例在手术后确诊。有 13 例存活婴儿,7 例早产儿(30.4%),6 例足月儿(26.1%)。新生儿并发症包括呼吸窘迫综合征(38.5%)和住院时间延长(46.2%)。产妇住院期间的并发症包括少尿(65.2%)、出血(30.4%)、重症监护病房停留时间延长(56.5%)和住院时间延长(26.2%)。院内死亡率为 8.7%。
在妊娠女性中紧急和急诊瓣膜置换术可以实现较好的母婴发病率和死亡率;然而,当手术在早期妊娠进行时,可能会出现较高的胎儿丢失率。