Grabowska Iwona, Singleton Daniel G, Stachyra Anna, Góra-Sochacka Anna, Sirko Agnieszka, Zagórski-Ostoja Włodzimierz, Radecka Hanna, Stulz Eugen, Radecki Jerzy
Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland.
Chem Commun (Camb). 2014 Apr 25;50(32):4196-9. doi: 10.1039/c4cc00172a.
We report the use of Co-porphyrins as electrochemical tags for a highly sensitive and selective genosensor. An avian influenza virus-based DNA sequence characteristic of H5N1 was detected at femtomolar levels from competing non-complementary sequences through hybridisation with the labeled DNA.
我们报道了使用钴卟啉作为电化学标签用于高灵敏度和选择性的基因传感器。通过与标记的DNA杂交,在飞摩尔水平从竞争性非互补序列中检测到了基于H5N1的禽流感病毒DNA序列特征。