Divine Laura M, Huh Warner K
*Department of Obstetrics and Gynecology †Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Clin Obstet Gynecol. 2014 Jun;57(2):316-24. doi: 10.1097/GRF.0000000000000020.
Human pappilomavirus (HPV) has been recognized as the most common sexually transmitted disease in the world and over 100 different HPV types have been identified. Persistent HPV infection has been closely linked to the development of invasive cervical cancer. Although surgical and ablative therapies have been the mainstay of treatment, vaccination against the main oncogenic type of HPV is a reasonable preventive strategy for HPV-induced cervical cancer.
人乳头瘤病毒(HPV)已被公认为世界上最常见的性传播疾病,并且已鉴定出100多种不同的HPV类型。持续性HPV感染与浸润性宫颈癌的发生密切相关。尽管手术和消融治疗一直是主要的治疗方法,但针对主要致癌类型的HPV进行疫苗接种是预防HPV诱发宫颈癌的合理策略。