Van Hede Dorien, Langers Inge, Delvenne Philippe, Jacobs Nathalie
University of Liège, cellular and molecular immunology, GIGA-Research, 4000 Liège, Belgium.
University of Liège, experimental pathology, GIGA-Research, 4000 Liège, Belgium.
Presse Med. 2014 Dec;43(12 Pt 2):e413-21. doi: 10.1016/j.lpm.2014.09.005. Epub 2014 Nov 4.
Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500,000 recorded cases. This review is focused on where and why HPV infection induces cervical cancers and how this virus avoids the host immune response. Immunological therapeutic approaches are also addressed.
人乳头瘤病毒相关子宫颈癌是一个重要的公共卫生问题，因为它被列为全球女性中第四大常见癌症，记录病例超过50万例。本综述重点关注人乳头瘤病毒感染诱发宫颈癌的部位及原因，以及该病毒如何逃避宿主免疫反应。还讨论了免疫治疗方法。
