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Understanding and targeting centrally mediated visceral pain in inflammatory bowel disease.

作者信息

Farrell Kristen E, Callister Robert J, Keely Simon

机构信息

School of Biomedical Sciences and Pharmacy, The University of Newcastle Callaghan, NSW, Australia.

School of Biomedical Sciences and Pharmacy, The University of Newcastle Callaghan, NSW, Australia ; Gastrointestinal Research Group, Viruses, Infection/Immunity, Vaccines and Asthma Program, Hunter Medical Research Institute New Lambton Heights, NSW, Australia.

出版信息

Front Pharmacol. 2014 Mar 5;5:27. doi: 10.3389/fphar.2014.00027. eCollection 2014.

DOI:10.3389/fphar.2014.00027
PMID:24634658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3942649/
Abstract
摘要

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The use of lipid-based nanocarriers for targeted pain therapies.基于脂质的纳米载体在靶向疼痛治疗中的应用。
Front Pharmacol. 2013 Nov 21;4:143. doi: 10.3389/fphar.2013.00143.
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A systematic review of the evidence for central nervous system plasticity in animal models of inflammatory-mediated gastrointestinal pain.炎症介导的胃肠道疼痛动物模型中中枢神经系统可塑性的证据的系统评价。
Inflamm Bowel Dis. 2014 Jan;20(1):176-95. doi: 10.1097/01.MIB.0000437499.52922.b1.
3
Extrinsic primary afferent signalling in the gut.肠道中的外感受性初级传入信号。
Nat Rev Gastroenterol Hepatol. 2013 May;10(5):286-96. doi: 10.1038/nrgastro.2013.29. Epub 2013 Feb 26.
4
New insights into the brain involvement in patients with Crohn's disease: a voxel-based morphometry study.对克罗恩病患者大脑受累的新认识：基于体素的形态计量学研究。
Neurogastroenterol Motil. 2013 Feb;25(2):147-e82. doi: 10.1111/nmo.12017. Epub 2012 Sep 23.
5
Pain management in patients with inflammatory bowel disease: insights for the clinician.炎症性肠病患者的疼痛管理：临床医生的见解。
Therap Adv Gastroenterol. 2012 Sep;5(5):339-57. doi: 10.1177/1756283X12446158.
6
Long-term sensitization of mechanosensitive and -insensitive afferents in mice with persistent colorectal hypersensitivity.持续结直肠高敏感小鼠机械敏感和非敏感传入纤维的长期致敏。
Am J Physiol Gastrointest Liver Physiol. 2012 Apr;302(7):G676-83. doi: 10.1152/ajpgi.00490.2011. Epub 2012 Jan 19.
7
Sprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivity.慢性内脏高敏感模型中小鼠结肠传入中枢末端发芽和脊髓丝裂原活化蛋白激酶表达增加。
J Comp Neurol. 2012 Jul 1;520(10):2241-55. doi: 10.1002/cne.23042.
8
Narcotic use for inflammatory bowel disease and risk factors during hospitalization.炎性肠病患者住院期间的麻醉药物使用和相关风险因素。
Inflamm Bowel Dis. 2012 May;18(5):869-76. doi: 10.1002/ibd.21806. Epub 2011 Jul 7.
9
Understanding and treating abdominal pain and spasms in organic gastrointestinal diseases: inflammatory bowel disease and biliary diseases.理解和治疗有机胃肠道疾病中的腹痛和痉挛：炎症性肠病和胆道疾病。
J Clin Gastroenterol. 2011 Aug;45 Suppl:S89-93. doi: 10.1097/MCG.0b013e31821fbd82.
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Impact of narcotic use on the requirement for colectomy in inpatients with ulcerative colitis.阿片类药物使用对溃疡性结肠炎住院患者结肠切除术需求的影响。
Dis Colon Rectum. 2010 Sep;53(9):1295-300. doi: 10.1007/DCR.0b013e3181e7562c.