Tatarinov Iu S, Zorin N a, Krivonosov S K, Pogorelova T Iu, Petrunin D D
Ontogenez. 1988 Sep-Oct;19(5):474-7.
The interaction between the fertility alpha 2-microglobulin and steroid sex hormones (estrone, estriol, estradiol, progesterone, testosterone) was studied by the use of cross immunoelectrophoresis with intermediate gels. alpha 2-microglobulin was shown to bind to the above hormones, its affinity to testosterone being the highest. The ability of alpha 2-microglobulin to bind to steroid hormones can be used for its isolation by affinity chromatography with immobilized steroid hormones.
采用带有中间凝胶的交叉免疫电泳法研究了生育α2-微球蛋白与甾体性激素(雌酮、雌三醇、雌二醇、孕酮、睾酮)之间的相互作用。结果表明,α2-微球蛋白能与上述激素结合,其中它对睾酮的亲和力最高。α2-微球蛋白与甾体激素的结合能力可用于通过固定化甾体激素亲和色谱法对其进行分离。