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[人胎盘特异性蛋白质系统的免疫化学研究]

[Immunochemical studies of the system of specific proteins of the human placenta].

作者信息

Tkachenko O A, Petrunin D D

出版信息

Vestn Ross Akad Med Nauk. 1995(3):40-4.

PMID:7540448
Abstract

The levels of placental lactogen, (PL), trophoblastic beta-globulin (TBG), placental alpha-microglobulin (PAMG-1), alpha 2-microglobulin of fertility (AMGF) in the blood serum of females, amniotic liquid and tissue of the placenta during pregnancy were comparatively studied and the protein-synthesizing function in the placenta in gestosis was evaluated. An original approach to differential assessment of the placental function was developed, by using the comprehensive serological immunochemical assay for placental proteins, which was based on concurrent immunodiffuse determination of PL, TBG, and enzyme immunoassay for AMGF and PAMG-1.

摘要

对孕期女性血清、羊水及胎盘组织中胎盘催乳素(PL)、滋养层β-球蛋白(TBG)、胎盘α-微球蛋白(PAMG-1)、生育α2-微球蛋白(AMGF)的水平进行了比较研究,并评估了妊娠中毒症时胎盘的蛋白质合成功能。通过使用基于同时免疫扩散法测定PL、TBG以及AMGF和PAMG-1的酶免疫法对胎盘蛋白进行综合血清免疫化学分析,开发了一种用于胎盘功能差异评估的原始方法。

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