Bardou A L, Degonde J, Birkui P J, Auger P, Chesnais J M, Duriez M
Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 256, Hôpital Broussais, Paris, France.
Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):1990-5. doi: 10.1111/j.1540-8159.1988.tb06339.x.
Reduction of energy required to defibrillate (ERD) seems to represent a necessary condition for intensive development of implantable defibrillator, so as for minimization of cardiac and pulmonary damages provoked by high energy transthoracic defibrillation electric shocks. The present work describes a defibrillation method using shocks delivered in orthogonal directions and separated by a 100 ms delay. Defibrillation threshold measured with classical unidirectional shocks on 30 dogs has been found to be 286.8 +/- 22.2 joules. In the same animals, defibrillation threshold measured by use of orthogonal shocks has been found to be 101.4 +/- 14.9 joules. We conclude that this crossed shocks method leads to a substantial reduction of ERD (64%).
降低除颤所需能量(ERD)似乎是植入式除颤器密集发展的必要条件,也是将高能经胸除颤电击引发的心脏和肺部损伤降至最低的必要条件。本研究描述了一种除颤方法,该方法使用在正交方向施加且间隔100毫秒延迟的电击。在30只狗身上使用经典单向电击测量的除颤阈值为286.8±22.2焦耳。在相同的动物中,使用正交电击测量的除颤阈值为101.4±14.9焦耳。我们得出结论,这种交叉电击方法可使ERD大幅降低(64%)。