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自动植入式心律转复除颤器(AICD)的适应症(患者选择):过去、现在与未来。

AICD indications (patient selection): past, present and future.

作者信息

Mower M M, Nisam S

机构信息

Sinai Hospital of Baltimore, Inc., Maryland 21215.

出版信息

Pacing Clin Electrophysiol. 1988 Nov;11(11 Pt 2):2064-70. doi: 10.1111/j.1540-8159.1988.tb06351.x.

DOI:10.1111/j.1540-8159.1988.tb06351.x
PMID:2463589
Abstract

During the course of a seven year implant experience with the Automatic Implantable Cardioverter-Defibrillator (AICD) now extending to well over 3,700 implantees, several functional advances have been made in the pulse generators, and criteria for implantation were successively broadened. Survival statistics have been excellent with 1-year arrhythmic survival over 98%, and total survival from all causes of death in excess of 60% at 5 years. Still, only relatively few of the patients who could possibly be helped by this device actually receive one. Reasons for this are probably complex but include, among other things, the relative newness of electrophysiology as a subspecialty, and a lack of appreciation by the general medical public in regard to this particular treatment modality. Small increases in referral patterns thus can have the potential to produce marked increases in the utilization of AICDs. Additionally, other high risk populations appear to be ready for inclusion into AICD therapeutic trials, and techniques also appear at hand to examine presumably healthy populations so as to predict those subject to suffer eventual sudden cardiac arrest. Under such circumstances, the ultimate impact of AICD therapy can hardly be imagined.

摘要

在长达七年使用植入式自动心脏除颤器(AICD)的经验过程中,目前植入者已超过3700人,脉冲发生器取得了多项功能进展,植入标准也相继放宽。生存统计数据非常出色,1年心律失常生存率超过98%,5年全因死亡率导致的总生存率超过60%。然而,实际上可能从该设备中受益的患者中只有相对较少的一部分真正接受了植入。原因可能很复杂,但其中包括电生理学作为一个亚专业相对较新,以及普通公众对这种特殊治疗方式缺乏认识。因此,转诊模式的小幅增加有可能显著提高AICD的利用率。此外,其他高风险人群似乎也准备好纳入AICD治疗试验,而且似乎也有技术可以检查大概健康的人群,以便预测那些最终会发生心脏骤停的人。在这种情况下,AICD治疗的最终影响几乎难以想象。

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