Vicente Emilio, Quijano Yolanda, Ielpo Benedetto, Duran Hipolito, Diaz Eduardo, Fabra Isabel, Oliva Catalina, Olivares Sergio, Caruso Riccardo, Ferri Valentina, Ceron Ricardo, Moreno Almudena
Hospital Universitario Madrid Sanchinarro, Centro Integral Oncológico Clara Campal, Facultad de Medicina, Universidad CEU San Pablo, Madrid, España.
Hospital Universitario Madrid Sanchinarro, Centro Integral Oncológico Clara Campal, Facultad de Medicina, Universidad CEU San Pablo, Madrid, España.
Cir Esp. 2014 May;92(5):305-15. doi: 10.1016/j.ciresp.2013.11.001. Epub 2014 Mar 15.
As surgical resection remains the only hope for cure in pancreatic cancer (PC), more aggressive surgical approaches have been advocated to increase resection rates. Venous resection demonstrated to be a feasible technique in experienced centers, increasing survival. In contrast, arterial resection is still an issue of debate, continuing to be considered a general contraindication to resection. In the last years there have been significant advances in surgical techniques and postoperative management which have dramatically reduced mortality and morbidity of major pancreatic resections. Furthermore, advances in multimodal neo-adjuvant and adjuvant treatments, as well as the better understanding of tumor biology and new diagnostic options have increased overall survival. In this article we highlight some of the important points that a modern pancreatic surgeon should take into account in the management of PC with arterial involvement in light of the recent advances.
由于手术切除仍是胰腺癌（PC）唯一的治愈希望，因此人们提倡采用更积极的手术方法来提高切除率。在经验丰富的中心，静脉切除已被证明是一种可行的技术，可提高生存率。相比之下，动脉切除仍是一个有争议的问题，仍然被视为手术切除的一般禁忌症。近年来，手术技术和术后管理取得了重大进展，显著降低了主要胰腺切除术的死亡率和发病率。此外，多模式新辅助和辅助治疗的进展，以及对肿瘤生物学的更好理解和新的诊断选择，提高了总体生存率。在本文中，我们根据最近的进展，强调现代胰腺外科医生在处理伴有动脉受累的胰腺癌时应考虑的一些要点。
