Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands.
Trends Plant Sci. 2014 May;19(5):288-91. doi: 10.1016/j.tplants.2014.02.003. Epub 2014 Mar 11.
The study of whole-genome sequences has become essential for almost all branches of biological research. Next-generation sequencing (NGS) has revolutionized the scalability, speed, and resolution of sequencing and brought genomic science within reach of academic laboratories that study non-model organisms. Here, we show that a high-quality draft genome of a eukaryote can be obtained at relatively low cost by exploiting a hybrid combination of sequencing strategies.
全基因组序列研究已经成为几乎所有生物学研究分支的必要手段。下一代测序（NGS）技术极大地提高了测序的可扩展性、速度和分辨率，使研究非模式生物的学术实验室能够开展基因组科学研究。在这里，我们展示了通过混合测序策略的组合，可以以相对较低的成本获得高质量的真核生物草图基因组。
