Departments of Dermatology and Pediatrics, Mayo Clinic, 200 First Street South West, Rochester, MN 55905, USA.
Pediatr Clin North Am. 2014 Apr;61(2):261-77. doi: 10.1016/j.pcl.2013.11.003. Epub 2013 Dec 31.
Psoriasis is increasing in both children and adults. The association of comorbidities, specifically obesity and other components of the metabolic syndrome, are also increasing. The precise cause is unknown but genetic and complex immunologic factors play a role in the development of the disease and its comorbidities. There are multiple clinical variants, and the severity of the disease can range from mild localized lesions in most patients to severe generalized involvement in some. Most patients with mild to moderate disease can be controlled with topical treatments.
银屑病在儿童和成人中的发病率都在增加。合并症的相关性，特别是肥胖症和代谢综合征的其他成分，也在增加。确切的病因尚不清楚，但遗传和复杂的免疫因素在疾病及其合并症的发展中起作用。有多种临床变异，疾病的严重程度可以从大多数患者的轻度局部病变到一些患者的严重全身性受累不等。大多数轻度至中度疾病患者可以通过局部治疗来控制。
