Institute of Solid Mechanics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.
Institute of Solid Mechanics, Technische Universität Braunschweig, 38106 Braunschweig, Germany; Institute of Mechanical Systems, ETH Zurich, 8092 Zurich, Switzerland.
Acta Biomater. 2014 Jul;10(7):3225-34. doi: 10.1016/j.actbio.2014.03.003. Epub 2014 Mar 14.
This paper deals with the role of the muscle fibres and extracellular matrix (ECM) components when muscle tissue is subjected to compressive loads. To this end, dissected tissue samples were tested in compression modes which induced states of fibres in compression (I), in tension (II) or at constant length (III), respectively. A comparison of the stress responses indicated that the tissue behaviour is significantly different for these modes, including differences between the modes (I) and (III). This contradicts the paradigm of many constitutive models that the stress response can be decomposed into an isotropic part relating to the ECM and an anisotropic fibre part the contribution of which can be neglected under compression. Conversely, the results provide experimental evidence that there is an anisotropic contribution of the fibre direction to the compressive stress. Interpreting these results in terms of recent microscopical studies, potential connections between the observed behaviour and the structure of muscle ECM are established.
本文探讨了肌肉组织受到压缩载荷时，肌纤维和细胞外基质（ECM）成分的作用。为此，分别对解剖组织样本进行了压缩测试，以诱导纤维处于受压（I）、受拉（II）或等长（III）状态。对这些状态下的应力响应进行比较，结果表明，组织的行为在这些模式下存在显著差异，包括模式（I）和（III）之间的差异。这与许多本构模型的范式相矛盾，这些模型认为，应力响应可以分解为与 ECM 相关的各向同性部分和各向异性纤维部分，在压缩下可以忽略后者的贡献。相反，结果提供了实验证据，表明纤维方向对压缩应力有各向异性的贡献。根据最近的微观研究，用这些结果来解释，观察到的行为与肌肉 ECM 的结构之间建立了潜在的联系。
