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半约束压缩实验中骨骼肌组织的长期力学行为

Long-term mechanical behaviour of skeletal muscle tissue in semi-confined compression experiments.

作者信息

Böl Markus, Leichsenring Kay, Ernst Michael, Ehret Alexander E

机构信息

Institute of Solid Mechanics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.

Institute of Solid Mechanics, Technische Universität Braunschweig, 38106 Braunschweig, Germany.

出版信息

J Mech Behav Biomed Mater. 2016 Oct;63:115-124. doi: 10.1016/j.jmbbm.2016.06.012. Epub 2016 Jun 17.

DOI:10.1016/j.jmbbm.2016.06.012
PMID:27367943
Abstract

In this study, porcine skeletal muscle tissue was tested until 112 hours post mortem using a semi-confined compression device that induces fascicles to enter one of the states of compression (mode I), tension (mode II), or constant length (mode III). Based on the authors׳ previous studies (Böl et al., 2014, 2015a), the anisotropic mechanical behaviour of the tissue was analysed, with a special focus on the testing time post mortem. The results suggest that the tissue exhibits significant anisotropic behaviour during the first hours of post mortem but that this anisotropy becomes insignificant at later time points. Interestingly, the compressibility of the tissue is more or less unaffected by the testing time. These results are discussed especially with respect to tissue microstructure.

摘要

在本研究中,使用半封闭式压缩装置对猪骨骼肌组织进行了长达死后112小时的测试,该装置可诱导肌束进入压缩状态(模式I)、拉伸状态(模式II)或恒定长度状态(模式III)之一。基于作者之前的研究(Böl等人,2014年、2015年a),分析了组织的各向异性力学行为,特别关注死后测试时间。结果表明,组织在死后最初几小时表现出显著的各向异性行为,但在随后的时间点这种各向异性变得不显著。有趣的是,组织的压缩性或多或少不受测试时间的影响。尤其结合组织微观结构对这些结果进行了讨论。

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