[基于海藻酸的含固定化特瑞利汀的多孔材料的制备]
[Preparation of porous material based on alginic acid, containing immobilized terrilytin].
作者信息
Komissarova A L, Iakubovidh V S, Tolstykh P I, Skokova I F, Virnik A D
出版信息
Antibiot Khimioter. 1988 Oct;33(10):735-9.
PMID:2463795
Abstract
A comparative study was conducted on immobilization of terrilytin on alginic acid by attaching the enzyme by ionic or covalent bonds and possible use of such compounds in preparing porous coatings for wound treatment. It was shown possible to prepare a coating with the enzyme activity after radiation sterilization equal to 80-85 per cent of the initial level. Medico-biological investigations proved that the use of the coating in treatment of purulent wounds was efficient.
摘要
通过离子键或共价键将terrilytin固定在海藻酸上，并研究此类化合物在制备用于伤口治疗的多孔涂层中的可能应用，进行了一项对比研究。结果表明，辐射灭菌后制备的具有酶活性的涂层，其活性相当于初始水平的80%至85%。医学 - 生物学研究证明，该涂层用于治疗化脓性伤口是有效的。
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