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含药吸收性材料对伤口愈合的影响

[The effect of absorbent materials with drugs on wound healing].

作者信息

Buianov V M, Egiev V N, Akimova A Ia, Gritskova I V

出版信息

Khirurgiia (Mosk). 1993 Nov(11):7-10.

PMID:7511713
Abstract

Absorptive hydrophilic materials (MAH) containing dioxydin and terrilytin as drug components were studied in experiments on guinea pigs infected with K-11 strain of E. coli. The results showed that the wounds in animals who did not receive treatment were cleaned by the 14th day, while the wounds in animals treated by applications of MAH with dioxydin and terrilytin became clean on the 3rd day, i. e. 5 times quicker. Absorptive hydrophilic materials containing dioxydin and teriilytin were easily handled, easily applied and removed, they did not injure the granulation tissue, and intensified growth of peripheral epithelialization. Thus, experimental study showed absorptive hydrophilic materials containing dioxydin and terrilytin to be highly effective in the treatment of purulent wounds, which allows them to be recommended for clinical use.

摘要

对含有地奥司明和特利立汀作为药物成分的吸收性亲水材料(MAH)进行了实验研究,实验对象是感染了大肠杆菌K - 11菌株的豚鼠。结果表明,未接受治疗的动物伤口在第14天得以清洁,而使用含有地奥司明和特利立汀的MAH进行治疗的动物伤口在第3天就变清洁了,即快了5倍。含有地奥司明和特利立汀的吸收性亲水材料易于操作,易于涂抹和去除,不会损伤肉芽组织,还能促进周边上皮化的生长。因此,实验研究表明含有地奥司明和特利立汀的吸收性亲水材料在治疗化脓性伤口方面非常有效,这使其可被推荐用于临床。

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