He Xiulan, Zhang Li, Qi Hetong, Yu Ping, Fei Junjie, Mao Lanqun
College of Chemistry, Xiangtan University, Xiangtan, Hunan 411105, China.
Analyst. 2014 May 7;139(9):2114-7. doi: 10.1039/c4an00124a.
We have demonstrated a new strategy to improve the fluorescence detection limit by enhancing the energy transfer efficiency between carbon structures and fluorescent dyes using polyimidazolium-functionalized carbon nanostructures as a low background signal platform. Based on this, a highly sensitive method for thrombin was proposed with a detection limit as low as 2.79 pM without any amplification.
我们展示了一种新策略,即通过使用聚咪唑功能化碳纳米结构作为低背景信号平台,提高碳结构与荧光染料之间的能量转移效率,从而改善荧光检测限。基于此,提出了一种用于凝血酶的高灵敏度方法,其检测限低至2.79 pM,无需任何放大。