Sharma S C, Berthoud V M, Breckwoldt R
Department of Ophthalmology, New York Medical College, Valhalla 10595.
J Comp Neurol. 1989 Jan 1;279(1):104-16. doi: 10.1002/cne.902790109.
Immunohistochemical methods were used to study the distribution of SP-like immunoreactivity (SPLI) in the brain of the common goldfish (Carassius auratus). SPLI cell bodies and fibers were seen in distant areas and nuclei throughout the brain. In the telencephalon, SPL1 was found in the area dorsalis telencephali pars centralis and pars lateralis, areas that have been compared to the basal ganglia of land vertebrates. In the diencephalon, SPLI somata were seen in the hypothalamus. Four primary visual centers contained SPLI fibers: the nucleus of the posterior commissure, the area pretectalis, the nucleus dorsolateralis thalami and the optic tectum; the origin of these fibers could not be determined. SPLI cell bodies were seen in the oculomotor nucleus; the possibility that this may be the Edinger-Westphal nucleus is discussed. A high density of immunoreactive fibers was seen in the tractus retroflexus and the interpeduncular nucleus, though the habenula showed a few SP-like immunopositive fibers. In the hindbrain, SPLI cell bodies and fibers were seen in the nuclei ambiguus and commissuralis of Cajal and in the dorsal motornucleus of the vagus nuclei; even though these nuclei are known to belong to the visceral and sensory motor columns, the exact role SP plays in processing this information is at present unknown.
采用免疫组织化学方法研究了普通金鱼（Carassius auratus）脑中P物质样免疫反应性（SPLI）的分布。在整个脑的不同区域和核团中均可见到SPLI细胞体和纤维。在端脑，SPL1存在于端脑背侧中央部和外侧部，这些区域可与陆地脊椎动物的基底神经节相比较。在间脑，下丘脑可见到SPLI细胞体。四个主要视觉中枢含有SPLI纤维：后连合核、顶盖前区、丘脑背外侧核和视顶盖；这些纤维的起源尚无法确定。动眼神经核中可见到SPLI细胞体；文中讨论了其可能为动眼神经副核的可能性。在缰核中虽可见到少量P物质样免疫阳性纤维，但在回返束和脚间核中可见到高密度的免疫反应性纤维。在后脑，疑核、Cajal连合核以及迷走神经背运动核中可见到SPLI细胞体和纤维；尽管已知这些核属于内脏和感觉运动柱，但目前P物质在处理这些信息中的确切作用尚不清楚。
