Schneider J, Vasung L, Truttmann A C, Huppi P S
Rev Med Suisse. 2014 Feb 19;10(418):442-9.
Due to advances in neonatal intensive care over the last decades, the pattern of brain injury seen in very preterm infants has evolved in more subtle lesions that are still essential to diagnose in regard to neurodevelopmental outcome. While cranial ultrasound is still used at the bedside, magnetic resonance imaging (MRI) is becoming increasingly used in this population for the assessment of brain maturation and white and grey matter lesions. Therefore, MRI provides a better prognostic value for the neurodevelopmental outcome of these preterms. Furthermore, the development of new MRI techniques, such as diffusion tensor imaging, resting state functional connectivity and magnetic resonance spectroscopy, may further increase the prognostic value, helping to counsel parents and allocate early intervention services.
由于过去几十年新生儿重症监护技术的进步，极早产儿脑损伤的模式已演变为更细微的损伤，而这些损伤对于神经发育结局的诊断仍然至关重要。虽然床边仍使用头颅超声，但磁共振成像（MRI）在这一人群中越来越多地用于评估脑成熟度以及白质和灰质病变。因此，MRI对这些早产儿的神经发育结局具有更好的预后价值。此外，诸如扩散张量成像、静息态功能连接和磁共振波谱等新MRI技术的发展，可能会进一步提高预后价值，有助于为家长提供咨询并分配早期干预服务。
