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神经影像学在预测早产儿神经发育结局中的作用。

The role of neuroimaging in predicting neurodevelopmental outcomes of preterm neonates.

作者信息

Kwon Soo Hyun, Vasung Lana, Ment Laura R, Huppi Petra S

机构信息

Department of Pediatrics, Yale University School of Medicine, 1 Park Street, West Pavilion, New Haven, CT 06510, USA.

The Division of Development and Growth, Department of Paediatrics, Children's Hospital Geneva, 6 rue Willy Donzé, 1211 Geneva, Switzerland.

出版信息

Clin Perinatol. 2014 Mar;41(1):257-83. doi: 10.1016/j.clp.2013.10.003. Epub 2013 Dec 12.

DOI:10.1016/j.clp.2013.10.003
PMID:24524459
Abstract

Magnetic resonance imaging (MRI) is a safe and high-resolution neuroimaging modality that is increasingly used in the neonatal population to assess brain injury and its consequences on brain development. It is superior to cranial ultrasound for the definition of patterns of both white and gray matter maturation and injury and therefore has the potential to provide prognostic information on the neurodevelopmental outcomes of the preterm population. Furthermore, the development of sophisticated MRI strategies, including diffusion tensor imaging, resting state functional connectivity, and magnetic resonance spectroscopy, may increase the prognostic value, helping to guide parental counseling and allocate early intervention services.

摘要

磁共振成像(MRI)是一种安全且高分辨率的神经成像方式,越来越多地用于新生儿群体,以评估脑损伤及其对脑发育的影响。在定义白质和灰质成熟及损伤模式方面,它优于头颅超声,因此有潜力提供有关早产儿神经发育结局的预后信息。此外,包括扩散张量成像、静息态功能连接和磁共振波谱等复杂MRI技术的发展,可能会增加其预后价值,有助于指导家长咨询并分配早期干预服务。

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