• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[不同品系小鼠骨髓组成、松果体及胸腺功能的衰老特性]

[The aging particularities of bone marrow composition, pineal gland and thymus functions in mice of different lines].

作者信息

Labunets I F

出版信息

Adv Gerontol. 2013;26(3):425-31.

PMID:24640688
Abstract

We investigated the amount of stromal precursor cells for colonies of fibroblasts (CFC-F) and progenitor cells for granulocyte-macrophage colonies (CFC-GM cells), blood content of thymulin and melatonin in bone marrow of young and old mice CBA/Ca and FVB/N lines. The CBA/Ca mice demonstrated only weak increasing amount of CFC-F and CFC-GM in bone marrow, but these indices in FVB/N mice are increased more significantly. Linear difference of age-related changes in the biological features of the cells of bone marrow are significantly associated with the characteristics and relationships of the function of epiphysis and the thymus in mice of different lines during aging.

摘要

我们研究了年轻和老年CBA/Ca及FVB/N品系小鼠骨髓中形成成纤维细胞集落的基质前体细胞（CFC-F）和形成粒细胞-巨噬细胞集落的祖细胞（CFC-GM细胞）的数量、胸腺素和褪黑素的血液含量。CBA/Ca小鼠骨髓中CFC-F和CFC-GM的数量仅呈微弱增加，但FVB/N小鼠的这些指标增加更为显著。不同品系小鼠衰老过程中骨髓细胞生物学特性的年龄相关变化的线性差异与骨骺和胸腺功能的特征及关系显著相关。

相似文献

1
[The aging particularities of bone marrow composition, pineal gland and thymus functions in mice of different lines].[不同品系小鼠骨髓组成、松果体及胸腺功能的衰老特性]
Adv Gerontol. 2013;26(3):425-31.
2
[Influence of the pineal gland's factors on the cell composition of the bone marrow in animals of different age in conditions of changed thymus functional state].[松果体因子对胸腺功能状态改变条件下不同年龄动物骨髓细胞组成的影响]
Adv Gerontol. 2011;24(1):54-60.
3
[The pineal gland's peptides factors and the rhythms of functions of the thymus and bone marrow in animals during aging].
Adv Gerontol. 2004;13:81-9.
4
[Circannual rhythms of bone marrow cell composition in animals during aging: the role of pineal factors].
Fiziol Zh (1994). 2007;53(6):52-9.
5
[Thymus and adaptive changes of bone marrow cell composition in animals of different age].
Adv Gerontol. 2011;24(2):207-15.
6
[Age-related characteristics of the melatonin-producing epiphyseal function in CBA mice immunized by T-dependent antigen].
Fiziol Zh (1994). 2005;51(4):45-50.
7
[Regulating effect of pineal gland peptides on development of T-lymphocytes in CBA aging mice: role of microenvironment of immune system organs and neuroendocrine factors].[松果体肽对CBA衰老小鼠T淋巴细胞发育的调节作用：免疫系统器官微环境及神经内分泌因子的作用]
Adv Gerontol. 2003;12:111-20.
8
[Thymic factors influence on melatonin-producing pineal function in mice of different age: the possible mechanisms].
Adv Gerontol. 2007;20(1):86-91.
9
Effects of bioactive factors of the pineal gland on thymus function and cell composition of the bone marrow and spleen in mice of different age.
Bull Exp Biol Med. 2004 May;137(5):510-2. doi: 10.1023/b:bebm.0000038166.54823.06.
10
[Biologically active thymic factors and melatonin-producing pineal function in mice in aging].
Fiziol Zh (1994). 2006;52(6):57-62.