Hussain Shabbir, Sabir Moin-ud-Din, Afzal Mohammad, Asghar Imran
J Pak Med Assoc. 2014 Feb;64(2):175-8.
To determine the incidence and pattern of various congenital heart disease in a neonatal unit of a tertiary care hospital.
The prospective study was carried out in the neonatal unit of Combined Military Hospital, Rawalpindi, from September 2008 to August 2011. All 5800 neonates admitted with gestational age of > 28 weeks irrespective of birthweight were included in the study. Neonatologist/Paediatrician carried out the neonatal examination during the first 12 hours of life. Neonates suspected of having congenital heart disease were further evaluated by pulse oxymetry, X-ray chest and echocardiography to ascertain final diagnosis and type of lesion. Data was collected on a predesigned proforma containing information regarding gender, mode of delivery, gestational age, weight at birth, family history, and associated malformations. SPSS 16 was used for statistical analysis.
Of the 5800 neonates, 87 (1.5%) were found to have congenital heart disease with an incidence of 15/1000. There was a male preponderance. Most common lesion was ventricular septal defect 27 (31.3%), followed by atrial septal defect 20 (22.9%), patent ductus arteriosus 13 (14.94%), tetralogy of fallot 06 (6.89%), transposition of great arteries 04 (4.59%), Pulmonary stenosis 05 (5.79%) and 03 (3.44%) had atrioventricular canal defects.
Congenital heart disease is a common congenital anomaly. Its incidence varies from centre to centre due to different factors like nature of the sample, method of detection and early examination by a neonatologist/paediatrician. In this study a higher incidence is reported because it was carried out in a tertiary care unit, which is a referral hospital and all the neonates admitted in the unit were included in the study.
确定一家三级护理医院新生儿科各种先天性心脏病的发病率及类型。
本前瞻性研究于2008年9月至2011年8月在拉瓦尔品第联合军事医院新生儿科开展。纳入所有胎龄>28周、不论出生体重的5800例新生儿。新生儿科医生/儿科医生在出生后12小时内进行新生儿检查。怀疑患有先天性心脏病的新生儿通过脉搏血氧测定、胸部X线和超声心动图进一步评估,以确定最终诊断及病变类型。数据收集在预先设计的表格上,内容包括性别、分娩方式、胎龄、出生体重、家族史及相关畸形。使用SPSS 16进行统计分析。
5800例新生儿中,87例(1.5%)被发现患有先天性心脏病,发病率为千分之十五。男性居多。最常见的病变是室间隔缺损27例(31.3%),其次是房间隔缺损20例(22.9%)、动脉导管未闭13例(14.94%)、法洛四联症6例(6.89%)、大动脉转位4例(4.59%)、肺动脉狭窄5例(5.79%)和房室通道缺损3例(3.44%)。
先天性心脏病是一种常见的先天性异常。由于样本性质、检测方法以及新生儿科医生/儿科医生的早期检查等不同因素,其发病率在不同中心有所差异。本研究报告的发病率较高,因为研究是在一家三级护理单位进行的,该单位是一家转诊医院,纳入了该单位收治的所有新生儿。