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种植体周围及部分缺牙区软组织增量的疗效:系统评价。

Efficacy of soft tissue augmentation around dental implants and in partially edentulous areas: a systematic review.

机构信息

Clinic of Fixed and Removable Prosthodontics and Dental Material Science, University of Zurich, Zurich, Switzerland.

出版信息

J Clin Periodontol. 2014 Apr;41 Suppl 15:S77-91. doi: 10.1111/jcpe.12220.

Abstract

AIM

To review the dental literature in terms of efficacy of soft tissue augmentation procedures around dental implants and in partially edentulous sites.

METHODS

A Medline search was performed for human studies augmenting keratinized mucosa (KM) and soft tissue volume around implants and in partially edentulous areas. Due to heterogeneity in between the studies, no meta-analyses could be performed.

RESULTS

Nine (KM) and eleven (volume) studies met the inclusion criteria. An apically positioned flap/vestibuloplasty (APF/V) plus a graft material [free gingival graft (FGG)/subepithelial connective tissue graft (SCTG)/collagen matrix (CM)] resulted in an increase of keratinized tissue (1.4-3.3 mm). Statistically significantly better outcomes were obtained for APF/V plus FGG/SCTG compared with controls (APF/V alone; no treatment) (p < 0.05). For surgery time and patient morbidity, statistically significantly more favourable outcomes were reported for CM compared to SCTGs (p < 0.05) in two randomized controlled clinical trials (RCTs), even though rendering less keratinized tissue. SCTGs were the best-documented method for gain of soft tissue volume at implant sites and partially edentulous sites. Aesthetically at immediate implant sites, better papilla fill and higher marginal mucosal levels were obtained using SCTGs compared to non-grafted sites.

CONCLUSIONS

An APF/V plus FGG/SCTG was the best-documented and most successful method to increase the width of KM. APF/V plus CM demonstrated less gain in KM, but also less patient morbidity and surgery time compared to APF/V plus SCTG based on two RCTs. Autogenous grafts (SCTG) rendered an increase in soft tissue thickness and better aesthetics compared to non-grafted sites.

摘要

目的

回顾有关牙种植体周围和部分缺牙区软组织增量程序疗效的牙科文献。

方法

对增加角化黏膜(KM)和种植体周围及部分缺牙区软组织体积的人类研究进行了 Medline 检索。由于研究之间存在异质性,因此无法进行荟萃分析。

结果

符合纳入标准的有 9 项(KM)和 11 项(体积)研究。一种牙冠向位瓣/成形术(APF/V)加移植物材料[游离龈移植(FGG)/黏膜下结缔组织移植(SCTG)/胶原基质(CM)]可增加角化组织(1.4-3.3mm)。与对照组(APF/V 单独;无治疗)相比,APF/V 加 FGG/SCTG 获得了统计学上更好的结果(p<0.05)。在两项随机对照临床试验(RCT)中,与 SCTG 相比,CM 在手术时间和患者发病率方面的结果更为有利(p<0.05),尽管获得的角化组织较少。SCTG 是在种植体部位和部分缺牙部位获得软组织量增加的最佳记录方法。在即刻种植体部位,与未移植部位相比,SCTG 获得了更好的乳头填充和更高的边缘黏膜水平,从而获得了更好的美学效果。

结论

APF/V 加 FGG/SCTG 是增加 KM 宽度的最佳记录和最成功的方法。基于两项 RCT,与 APF/V 加 SCTG 相比,APF/V 加 CM 在获得 KM 方面的增益较少,但患者发病率和手术时间也较少。与未移植部位相比,自体移植物(SCTG)可增加软组织厚度并改善美学效果。

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