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文莱达鲁萨兰国的肾脏替代治疗:与国际肾脏登记处比较标准

Renal replacement therapy in Brunei Darussalam: comparing standards with international renal registries.

作者信息

Tan Jackson

机构信息

Rimba Dialysis Centre, Department of Renal Services, Bandar Seri Begawan, Brunei Darussalam.

出版信息

Nephrology (Carlton). 2014 May;19(5):288-95. doi: 10.1111/nep.12228.

Abstract

BACKGROUND AND AIM

Brunei Darussalam is a small South East Asian country with a high prevalence and incidence of end stage kidney disease (ESRD). This study aims to compare key performance indicators recorded in the Brunei Dialysis and Transplant Registry and department records against international practice. Registries from the USA (USRDS), UK (UK Renal Registry), Australasia (ANZDATA), Europe (ERA-EDTA Registry) and Malaysia (MDTR) were used for comparisons.

METHODS AND RESULTS

Haemodialysis (83%) and renal transplantation (6%) were the most and least favoured modality of renal replacement therapy in Brunei. Diabetes mellitus as a cause of ESRD (57%) was high in Brunei but on par with other South East Asian countries. Dialysis death rates (11%) and living-related transplant survival rates (5 year graft and patient survival 91% and 96% respectively) were favourable compared with other registries. Anaemia and mineral bone disease management were similar to Malaysia but slightly inferior to the others, but generally in keeping with KDOQI and KDIGO targets. Haemodialysis adequacy (48% achieving urea reduction ratio of >65%) was relatively poorer due to poor dialysis flow rates and low fistula usage (71%). Peritoneal dialysis peritonitis (24.5 patient-month/episode) and adequacy (78% achieving kt/v of 1.7) were in keeping with ISPD targets and international registries' results.

CONCLUSION

Brunei has achieved reasonable and commendable standards in many areas pertaining to the renal services. This report has identified several key areas for developments but this is to be expected for a service making its first foray into international benchmarked practice.

摘要

背景与目的

文莱达鲁萨兰国是东南亚的一个小国,终末期肾病(ESRD)的患病率和发病率很高。本研究旨在将文莱透析与移植登记处及科室记录中的关键绩效指标与国际惯例进行比较。使用了来自美国(美国肾脏数据系统)、英国(英国肾脏登记处)、澳大拉西亚(澳新透析和移植登记处)、欧洲(欧洲肾脏协会-欧洲透析和移植协会登记处)和马来西亚(马来西亚透析和移植登记处)的登记数据进行比较。

方法与结果

血液透析(83%)和肾移植(6%)是文莱最常用和最不常用的肾脏替代治疗方式。文莱因糖尿病导致的ESRD比例(57%)较高,但与其他东南亚国家相当。与其他登记处相比,透析死亡率(11%)和亲属活体移植存活率(5年移植肾和患者存活率分别为91%和96%)较为理想。贫血和矿物质骨病的管理与马来西亚相似,但略逊于其他国家,但总体上符合美国肾脏病预后质量倡议(KDOQI)和改善全球肾脏病预后组织(KDIGO)的目标。由于透析血流量低和内瘘使用率低(71%),血液透析充分性(尿素清除率>65%的患者占48%)相对较差。腹膜透析腹膜炎发生率(每24.5患者月/次)和充分性(kt/v达到1.7的患者占78%)符合国际腹膜透析协会(ISPD)的目标和国际登记处的结果。

结论

文莱在肾脏服务的许多领域已达到合理且值得称赞的标准。本报告确定了几个关键的发展领域,但对于首次涉足国际基准实践的服务来说,这是可以预料的。

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