Akhavan Ardavan, Avery Daniel, Lendvay Thomas S
Division of Pediatric Urology, Seattle Children's Hospital, 4800 Sand Point Way, NE, Seattle, WA 98105, USA.
Division of Pediatric Urology, Seattle Children's Hospital, 4800 Sand Point Way, NE, Seattle, WA 98105, USA.
J Pediatr Urol. 2014 Oct;10(5):864-8. doi: 10.1016/j.jpurol.2014.01.028. Epub 2014 Mar 6.
Extravesical robot-assisted laparoscopic ureteral reimplantation (RALUR) is a popular alternative to open surgery. We report our experience with RALUR and evaluate clinical variables as predictors for failure.
We retrospectively evaluated the records of patients who underwent RALUR by a single surgeon for treatment of primary vesicoureteral reflux. Clinical and demographic variables were determined. Clinical variables were compared with surgical outcomes using the Student two-tailed type 2 t test.
Fifty patients underwent a combined 78 extravesical RALURs. Median (range) age was 6.2 (1.9-18.0) years; median (range) preoperative reflux grade was 3 (0-5). Dysfunctional elimination syndrome (DES) was present in 32 (64%). Ten (20%) patients had prior deflux, and two (4%) had prior ureteroneocystostomy on the ipsilateral side. Postoperative cystogram was performed in 100% at a median (range) of 55 (27-133) days. Median (range) follow-up was 286 (27-2238) days. Febrile urinary tract infection occurred in five (10%), none of whom had reflux on initial follow-up postoperative cystogram. All five had a history of DES and were female. Six complications occurred in five (10%) patients, including ileus (2), ureteral obstruction (2), ureteral injury (1), and perinephric fluid collection (1). Transient urinary retention occurred in one. Five of 22 (22.7%) patients undergoing unilateral surgery had contralateral de novo reflux. Six of 78 ureters (7.7%) had persistent reflux postoperatively. Neither persistent nor de novo reflux was associated with any of the clinical variables assessed.
RALUR is an effective and safe option for patients with primary vesicoureteral reflux requiring surgery.
膀胱外机器人辅助腹腔镜输尿管再植术(RALUR)是开放手术的一种常用替代方法。我们报告我们的RALUR经验,并评估临床变量作为失败的预测因素。
我们回顾性评估了由单一外科医生进行RALUR治疗原发性膀胱输尿管反流的患者记录。确定了临床和人口统计学变量。使用学生双尾2型t检验将临床变量与手术结果进行比较。
50例患者共接受了78次膀胱外RALUR。中位(范围)年龄为6.2(1.9 - 18.0)岁;术前反流分级中位(范围)为3(0 - 5)。32例(64%)存在排尿功能障碍综合征(DES)。10例(20%)患者曾接受过注入治疗,2例(4%)同侧曾接受过输尿管膀胱吻合术。100%的患者在中位(范围)55(27 - 133)天进行了术后膀胱造影。中位(范围)随访时间为286(27 - 2238)天。5例(10%)发生发热性尿路感染,初次术后随访膀胱造影时均无反流。所有5例均有DES病史且均为女性。5例(10%)患者发生6例并发症,包括肠梗阻(2例)、输尿管梗阻(2例)、输尿管损伤(1例)和肾周积液(1例)。1例发生短暂性尿潴留。22例接受单侧手术的患者中有5例(22.7%)出现对侧新发反流。78条输尿管中有6条(7.7%)术后持续反流。持续性反流和新发反流均与所评估的任何临床变量无关。
对于需要手术的原发性膀胱输尿管反流患者,RALUR是一种有效且安全的选择。