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睡眠障碍遗传学综述。

A review on genetics of sleep disorders.

作者信息

Bidaki Reza, Zarei Mina, Khorram Toosi Ali, Hakim Shooshtari Mitra

机构信息

Department of psychiatry Rafsanjan University of medical sciences, Rafsanjan, Iran.

Tehran University of Medical Science. Tehran, Iran.

出版信息

Iran J Psychiatry Behav Sci. 2012 Spring;6(1):12-9.

Abstract

One-third of population deal with sleep disorders which might be due to social, economic or medical problems. Studies on twins have indicated the role of genetic factors in these disorders. Monozygotic twins have a very similar hypnogram. A higher prevalence of some sleep disorders is reported in relatives of the patients with these disorders. Genes also affect sleep disorders as well as some other disorders at the same time. Sleep disorders can also influence the level of the personal and social functioning. Recent genetic advances have clarified the role of different genes in sleep disorders. The purpose of this article is to present a brief review about the role of genetic factors in some of the sleep disorders.

摘要

三分之一的人患有睡眠障碍,这可能是由社会、经济或医学问题引起的。对双胞胎的研究表明了遗传因素在这些障碍中的作用。同卵双胞胎有非常相似的睡眠图。据报道,患有这些睡眠障碍的患者的亲属中,某些睡眠障碍的患病率更高。基因同时也会影响睡眠障碍以及其他一些疾病。睡眠障碍也会影响个人和社会功能水平。最近的遗传学进展已经阐明了不同基因在睡眠障碍中的作用。本文的目的是简要综述遗传因素在某些睡眠障碍中的作用。

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本文引用的文献

1
Genetic aspects of normal and disturbed sleep.正常睡眠与睡眠障碍的遗传学方面
Sleep Med. 2009 Sep;10 Suppl 1:S17-21. doi: 10.1016/j.sleep.2009.07.002. Epub 2009 Aug 5.
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The genetic basis of sleep disorders.
Curr Pharm Des. 2008;14(32):3386-95. doi: 10.2174/138161208786549308.
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The genetics of sleep disorders in childhood and adolescence.
J Pediatr (Rio J). 2008 Aug;84(4 Suppl):S27-32. doi: 10.2223/JPED.1786. Epub 2008 Aug 29.
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Genetics of sleep and sleep disorders.睡眠与睡眠障碍的遗传学
Cell Mol Life Sci. 2007 May;64(10):1216-26. doi: 10.1007/s00018-007-6532-1.

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