Zaheryany Seyed Mohammad Salar, Bidaki Reza, Hemmatian Brujeni Nahid, Rezvani Mohammad, Hakim Shooshtari Mitra
Tehran University of Medical Sciences, Tehran, Iran.
MD. Assistant Professor of Psychiatry, Rafsanjan University of Medical Science Department of Psychiatry, Rafsanjan, Iran.
Iran J Psychiatry Behav Sci. 2012 Fall;6(2):96-9.
We present a 19-year-old patient with hematologic and neurologic manifestations associated with Wilson's disease. Idiopathic thrombocytopenia was diagnosed in October 2009. Bone marrow aspiration was normal. Gradually her neurologic and psychiatric symptoms emerged, dysarthria, writing apraxia, learning difficulties, emotionalism and eventually dystonia of hands. The serum ceruloplasmin was low, and the Kayser Fleischer's ring was positive. MRI of the brain showed abnormality in the bilateral basal ganglia, brain stem and superior cerebellar peduncles without post-contrast enhancement.
我们报告一名19岁患有与威尔逊病相关的血液学和神经学表现的患者。2009年10月诊断为特发性血小板减少症。骨髓穿刺结果正常。逐渐地，她出现了神经和精神症状，构音障碍、书写失用症、学习困难、情绪不稳定，最终出现手部肌张力障碍。血清铜蓝蛋白水平低，且凯-弗环阳性。脑部MRI显示双侧基底神经节、脑干和小脑上脚异常，增强扫描后无强化。
