肾病理学家需要了解的抗磷脂综合征相关性肾病：是时候制定肾脏形态学病变的分类了吗？
What nephrolopathologists need to know about antiphospholipid syndrome-associated nephropathy: Is it time for formulating a classification for renal morphologic lesions?
作者信息
Mubarak Muhammed, Nasri Hamid
机构信息
Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan.
Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Nephropathol. 2014 Jan;3(1):4-8. doi: 10.12860/jnp.2014.02. Epub 2014 Jan 1.
CONTEXT
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder which commonly affects kidneys.
EVIDENCE ACQUISITIONS
Directory of Open Access Journals (DOAJ), Google Scholar, PubMed (NLM), LISTA (EBSCO) and Web of Science have been searched.
RESULTS
There is sufficient epidemiological, clinical and histopathological evidence to show that antiphospholipid syndrome is a distinctive lesion caused by antiphospholipid antibodies in patients with different forms of antiphospholipid syndrome. It is now time to devise a classification for an accurate diagnosis and prognostication of the disease.
CONCLUSIONS
Now that the morphological lesions of APSN are sufficiently well characterized, it is prime time to devise a classification which is of diagnostic and prognostic utility in this disease.
背景
抗磷脂综合征（APS）是一种常见影响肾脏的系统性自身免疫性疾病。
证据获取
检索了开放获取期刊目录（DOAJ）、谷歌学术、PubMed（美国国立医学图书馆）、LISTA（EBSCO）和科学引文索引。
结果
有充分的流行病学、临床和组织病理学证据表明，抗磷脂综合征是不同形式抗磷脂综合征患者中由抗磷脂抗体引起的一种独特病变。现在是时候设计一种分类方法以准确诊断和预测该疾病了。
结论
鉴于抗磷脂综合征肾病（APSN）的形态学病变已得到充分表征，现在是设计一种对该疾病具有诊断和预后价值的分类方法的最佳时机。
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